In infected mussels, the great majority of DEGs were included in metabolism pathways known to be greatly affected by immune challenges and in pathways related to translation, signal transduction (phosphatidylinositol signaling system, the mTOR signaling pathway and the PI3K-Akt signaling pathway), viral infectious diseases and immune system (defense cells differentiation and signaling) (Supplementary File 1). The gene discussed is MTOR; the disease is viral infectious disease.