To determine whether the NF-κB transcription factors are responsible for the enhanced expression of CADM1 in ATLL cells, we treated the MT2/HTLV-1-infected T-cell line and KK1/ATLL-derived cell line with the NF-κB inhibitor BAY11-7082 and analyzed for EMSA using probe A or B and the expression of CADM1 by real-time RT-PCR analysis. This evidence concerns the gene CADM1 and adult T-cell leukemia/lymphoma.