CADM1 and adult T-cell leukemia/lymphoma: In probes A and B, the shifted bands corresponding to the DNA-protein complex were clearly detected in nuclear lysates from two ATLL cell lines but were not or weakly detected in the no lysate control or lysate from MOLT4 cells (Fig. 2B), suggesting that the sequence covered by the probes A and B might be responsible for the transcriptional activation of the CADM1 promoter in ATLL cells.