For example, rs7749390 an intronic variant in the IFNGR1 gene (Table 2, Fig. 2d) and rs3764613 within PPP5C (Table 2, Fig. 2e), showed very strong evidence for associations with mouth ulcers (OR 1.08, 95% CI: 1.07, 1.08; EAF 0.61; P = 2.0e−62 and OR 0.93, 95% CI: 0.92, 0.93; EAF 0.43; P = 7.4e−73, respectively). Here, IFNGR1 is linked to Oral ulcer.