IL10 and Oral ulcer: rs1800871, a variant within 1 kb 5′ of IL10, showed the second strongest evidence for association after meta-analysis, conferring a large effect on mouth ulcers (OR 1.18 per A allele, 95% CI: 1.17, 1.19; EAF 0.22; P = 6.0e−236) (Table 2, Fig. 2b).