Therefore, in contrary to induced pluripotent stem cells (iPS) cells that are known to induce multiple teratoma growth [73, 74], in case of human MSC, so far, there is not enough evidence to suggest that application of extensively expanded MSC populations which might be enriched in c-MYC-overexpressing cells should be hindered by increased tumorigenesis risk. Here, MYC is linked to teratoma.