In addition, we also make experiments to confirm the following: whether differential expression of lncRNAs in our screen was gender dependent, whether SLE patients exhibited a robust or weak “IFN signature,” and whether PBMCs from SLE patients (as compared with healthy donors) exhibited differential expression of lncRNAs due to a change in the number of a cell type (e.g., lymphocytes, monocytes, and DCs) in peripheral blood. The gene discussed is IFNA1; the disease is systemic lupus erythematosus.