Interferon-induced protein with tetratricopeptide repeats 3 (IFIT3) is one of the genes which contribute to the overactive cGAS-STING signaling pathway in SLE monocytes, which may serve as a therapeutic target to block the production of type I IFN and other pro-inflammatory cytokines by cGAS-STING signaling pathway [49]. Here, CGAS is linked to systemic lupus erythematosus.