Wu et al. reported the significant downregulation of linc0949 and linc0597 in peripheral blood mononuclear cells (PBMCs) of patients with SLE; the results also indicated that linc0949 expression was negatively correlated with the degree of disease activity and organ damage but positively correlated with complement C3 level [9]. This evidence concerns the gene C3 and systemic lupus erythematosus.