In univariate analyses (Table 2), we discovered that significant differences existed among groups in age (p < .001), EF (p < .001), Nt-ProBNP (p < .001), creatinine clearance (p < .001), coronary artery stenosis severity (p < .001), medical history of hypertension (p = .003) or diabetes (p < .001), prescription of loop diuretics (p < .001) or aldosterone receptor antagonist (p < .001), depression severity (p < .001), somatic (p < .001) and cognitive (p < .001) depressive symptoms, but not in anxiety severity (p = 0.99), type of AP (p = 0.24), nor education background (p = 0.83). Here, NR3C2 is linked to major depressive disorder.