CCN1 and colorectal neoplasm: The list also included one for cadherin 7, involved in calcium-dependent cell-cell adhesion [35], one for L1CAM, overexpression of which in colorectal tumor was previously associated with shorter survival [42], one for proteoglycan versican and one for CYR61, cysteine-rich angiogenic inducer 61, known biomarkers of colorectal cancer [43, 44].