In this regard, Barrera-Ramirez J et al. demonstrated that the profile of EV miRNAs from MSCs derived from in patients with AML was analyzed by RNA sequencing and found that some of miRNAs such as miR-26a-5p and miR-101-3p were significantly increased concomitant with reduction of EZH2 and GSK3β mRNA. This evidence concerns the gene GSK3B and acute myeloid leukemia.