The PI3K (phosphatidylinositol-4,5-bis-phosphate 3-kinase)/Akt(v-akt murine thymoma viral oncogene homolog) pathway is involved in cell survival, proliferation, and metabolism, and is commonly associated with harmful modification processes in a variety of cancers, including kidney (Linehan et al. 2010). This evidence concerns the gene AKT1 and cancer.