Hypoxia‐inducible factor‐1α regulates VEGF expression at the transcriptional level.13 In the present study, we identified miR‐148a, which may be related to tumour angiogenesis; identified the signalling pathways that are regulated by miR‐148a; and determined the role of miR‐148a in the angiogenesis of CRC. The gene discussed is VEGFA; the disease is colorectal carcinoma.