Previous study investigated the incidence and prevalence of GATA4, NKX2‐5, gene mutations in a large group of individuals with controtruncal defect (CTD), including 178 patients with tetralogy of Fallot, 13 patients with double–outlet right ventricle (DORV), and 11 patients with truncus arteriosus. Here, NKX2-5 is linked to Tetralogy of Fallot.