CLEC5A and chronic obstructive pulmonary disease: CLEC5A, a type II transmembrane protein, was recently reported to have critical function in response to dengue virus,31 Japanese encephalitis virus32 and Listeria monocytogenes.31 Apart from these acute inflammatory diseases, CLEC5A was implicated in the progression of multiple chronic inflammatory diseases, such as autoimmune arthritis33 and chronic obstructive pulmonary disease (COPD).31 Several studies revealed that exaggerated cytokine released from CLEC5A‐expressing cells in respective pathologies.