CASP3 and breast carcinoma: In addition, ADMC added to the SK-BR-3 over 4 days revealed significant (p = 0.003) breast cancer cell death, but not ADMC death (anti-tryptase labeled), as indicated by immunostaining of the SK-BR-3 with an Ab specific for the apoptotic enzyme caspase 3 (Figures 5C,D).