JMY and cancer: JMY is thought to play a dual role in cancer biology by having both a tumor suppressive capacity in the setting of DNA damage where it enhances P53 activity and a tumor metastasis promoter due to its ability to nucleate actin filament.29 Our microarray analysis shows a significant and greater than 2-fold increase in TP531NP expression which suggests that the upregulation of JMY may have been modulating P53 activity in this cell line under the influence of the BFA.