Although the EGFR dynamics cannot differentiate the cancerous MCF7 cell from the non-tumorigenic MCF10A cell, a clear discrimination of the MDA-MB-231 and BT549 cells (highly invasive) from the MCF7, BT474, SKBR3, and MDA-MB-468 cells (non- to less invasive) is a remarkable evidence that the changes of TReD can be a signature of increased cancer invasiveness. This evidence concerns the gene EGFR and cancer.