To elucidate the connections among EGFR dynamics, PM compartmentalization, and invasiveness of cancer cells, we have performed the TReD assay on EGFRs in seven breast epithelial cell lines: MCF10A, MCF7, BT474, SKBR3, MDA-MB-468, MDA-MB-231, and BT549. This evidence concerns the gene EGFR and cancer.