miR-31 [45] and miR-221 [46], along with miR-222 [46], were verified as upstream of the AT-rich interactive domain-containing protein 1A (ARID1A), which is involved in the SWI/SNF family and recognized as a tumor suppressor in cancer through multiple kinds of pathways, such as p53 and PI3K/AKT pathways [47]. Here, AKT1 is linked to neoplasm.