Planned post-hoc comparisons between groups found that Braak B0 had a higher baseline MMSE compared to B1 (Z=2.4, p=0.02) and to the combined GT-38 AD-tau co-pathology group (i.e. B1-3 n=27, median/IQR=26.0/23.0-28.0 ; Z=2.2, p=0.03). This evidence concerns the gene MAPT and Alzheimer disease.