SLC7A7 and lysinuric protein intolerance: As a consequence, the decreased plasma levels and increased leakage in the urines of CAA, as observed in LPI patients, are usually referred to an impairment of transport activity consequent to the mutation of SLC7A7, implying that y + LAT1 is the transporter active in these cells; no study, however, has thus far addressed the relative expression of the genes coding for the two alternative light chains of system y+L in these tissues.