The amount of NFATc1+ osteoclasts per ROI were found to be significantly higher in MRONJ (BP) specimens (median: 25.1 osteoclasts/mm2) than in ORN (median: 1.8 osteoclasts/mm2; p < 0.022), OM (median: 0.0 osteoclasts/mm2; p < 0.004), and control specimens (median: 0.0 osteoclasts/mm2; p < 0.001) (Table 2; Fig. 2c). The gene discussed is NFATC1; the disease is ocular melanoma.