In that study, PBMC miR-148b is upregulated in IgA nephropathy; miR-148b targets the enzyme core 1, β1,3-galactosyltransferase-1, modulates IgA1 O-glycosylation as well as the levels of secreted galactose-deficient IgA1 [6]. This evidence concerns the gene IGHA1 and IgA glomerulonephritis.