EIF4E and melanoma: Our results are also concordant with recent findings by other groups who established that inhibition of eIF4E phosphorylation by Mnk1/2 inhibitors suppressed growth of diffuse large cell B-cell lymphoma and TNBC MDA-MB-231 tumor xenografts [23], cell-line and patient-derived non-small cell lung cancer xenografts [44] and metastasis of KIT-mutant melanoma [67].