SPCS2 and parathyroid gland adenoma: The most significant PPI sub-module was selected from sub-modules sorted by interaction score using clustering analysis (Figure 1); it included eight hub molecules (SPCS2, RPL23, RPL26, RPN1, SEC11C, SEC11A, RPS25, SEC61G), which suggests these hub molecules might play crucial roles in development of parathyroid adenoma.