The same association of rs4958351 in the GRIA1 gene with an asparaginase allergy in pediatric ALL patients was confirmed in another GWAS study, with the additional observation that the risk of allergy was higher in patients treated with native E. coli asparaginase than in patients treated with PEGylated E. coli asparaginase [77]. The gene discussed is ASPG; the disease is Allergy.