NES and glioblastoma: Notch2 expression levels in Glioblastoma tissue correlate with stemness genes (nestin, SOX2), astrocyte fate genes (vimentin and GFAP), and anti-apoptotic proteins (BCL6 and BCL-W), but are inversely correlated with Olig2, CNP, and PLP1 (oligodendrocyte fate) and pro-apoptotic proteins (BAX and BCLAF1) [102,103].