Cataract surgery was reported to cause an increase in choroidal thickness.20 The drop in intraocular pressure and rise in ocular perfusion pressure accompanied by increased choroidal thickness may be associated with increased inflammation due to elevated prostaglandin and cytokines, which are thought to cause cystoid macular edema in the retina.19,20,21,22 However, in our study, there was no significant difference in choroidal thickness between the patients who did and did not have cataract surgery, and choroidal thickness decreased in both groups due to anti-VEGF use. This evidence concerns the gene VEGFA and cystoid macular edema.