IL6 and metabolic dysfunction-associated steatohepatitis: Using an antibody enzyme‐linked immunosorbent assay (ELISA), serum CK18 levels can be measured sensitively; however, their clinical application is premature.26, 49 Inflammation is also a histological hallmark of NASH, and many inflammatory markers and mediators could serve as biomarkers of NASH, including tumor necrosis factor (TNF), interleukin‐6 (IL‐6), IL‐8, and C‐reactive protein (CRP).