CCL2 and steatosis: Furthermore, IR is always linked to chronic mild inflammation, and lots of regulators released by adipocytes or immune cells can in turn promote IR, including TNFα, IL‐6, IL‐1 and monocyte chemoattractant protein‐1 (MCP‐1, also known as CCL2) as well as the IKK/NF‐κB pathway.8, 157, 158 Steatosis, inflammation which are two important progresses of NAFLD are both linked with IR closely.