CFH was also reported to be associated with lung cancer.46 CR1 plays a crucial role in carcinogenesis and has been proved to be associated with an increased risk of developing non‐small cell lung cancer in Chinese population.47 LILRB2 is also suggested to be important for lung cancer development.48 ITGAX has been confirmed to be a biomarker for noninvasive molecular diagnosis of lung cancer.49 In contrast, only 28 out of the 52 genes and 50 out of the 240 genes identified by CovEx and HotNet2 are NCG cancer genes, respectively. This evidence concerns the gene CFH and cancer.