Despite the facts that survivin has been considered as an important signaling molecule in the pathogenesis of numerous autoimmune inflammatory diseases, or its increased expression is confirmed in leukocytes infiltrating ulcerative colitis and lung tissue in cystic fibrosis (Gravina et al., 2017), a potential role of survivin in hepatocytes and lymphocytes survival in sepsis still remains unclear. Here, BIRC5 is linked to Sepsis.