LINC00460, located at human chromosome 13q33.2, has been reported to be involved in tumor progression in multiple types of cancer.10, 11, 12, 13, 14, 15, 16 For example, Lian et al10 reported that LINC00460 promoted cell proliferation and inhibited apoptosis by regulating KLF2 and CUL4A expression in colorectal cancer. The gene discussed is CUL4A; the disease is colorectal cancer.