Furthermore, recent findings from the Norfolk Arthritis Register (NOAR) and Early RA Study cohorts demonstrated that HLA-DRB1 amino acids associated with RA susceptibility and radiographic joint damage were associated with SJC28 and CRP, but not 28 tender joint count (TJC28) (GHVAS was not assessed) [19]. Here, HLA-DRB1 is linked to rheumatoid arthritis.