TGFB1 and neoplasm: Indeed, non-immune stromal cells in the VPr tumor expressed significantly more Tgfb1 and Tgm2 (encoding a collagen crosslinking enzyme), and scored high for a fibroblast transforming growth factor-β response signature (PMID: 29443960), which included genes related to myofibroblast function (Extended Data Fig. 5c).