The mice with mild NAFLD were treated with vehicle for 21 days, while the mice with severe NAFLD were randomly divided into four groups, treated with either vehicle, GIP receptor agonist, GLP‐1 receptor agonist, or GIP/GLP‐1 co‐receptor agonist for 15 days while maintaining a high‐fat diet. This evidence concerns the gene GIP and metabolic dysfunction-associated steatotic liver disease.