These autoantibodies include antinuclear Abs (ANA), Abs to dsDNA, Sm, nuclear ribonucleoprotein, Ro, La, and phospholipids in SLE (1); rheumatoid factor and Abs to cyclic citrullinated peptides in RA (2); and Abs to insulin, glutamic acid decarboxylase (GAD65), the 40K fragment of tyrosine phosphatase (IA2), and zinc transporter 8 (ZnT8) in T1D (3). The gene discussed is BTG3; the disease is systemic lupus erythematosus.