PTEN and neoplasm: c, PTEN intact cases showed two CEP10 signals and two PTEN signal in tumor cells; d-e, The representative cases for PTEN homozygous deletion displayed PTEN/CEP10 ratio = 0.63 with two CEP10 signals and one PTEN signal in 80% of nuclei and PTEN/CEP10 ratio = 0.17 with two CEP10 signals and no PTEN signal in 70% of nuclei in NSCLC patients, respectively; f, One CEP10 and one PTEN signal in 70% of nuclei is considered as whole chromosome 10 deletion.