Since HOXD-AS1 was determined to enrich in nucleus of CRC cells by RNA fraction assays (Fig. 1c), a similar subcellular location for HOXD-AS1 in CRC cells was confirmed by FISH (Fig. 3d), which is consistent with a potential role for HOXD-AS1 in epigenetic or transcriptional regulation. Here, HAGLR is linked to colorectal carcinoma.