Gingerol might induce apoptosis both in vitro, using PC-3 prostate cancer cells, and in vivo, using mice with prostate cancer xenografts, by increasing the level of cleaved Poly (ADP-ribose) polymerase (PARP) and reducing the levels of anti-apoptotic protein Bcl-2 [71]. This evidence concerns the gene BCL2 and prostate carcinoma.