In prostate cancer cells, gallic acid reduced the levels of the following proteins: son of sevenless homolog 1 (SOS1), growth factor receptor bound protein 2 (GRB2), protein kinase C (PKC), NF-κB, c-Jun N-terminal kinase (JNK), ERK1/2, p38-MAPK, and p-Akt (Thr308, Ser 473) [133]. This evidence concerns the gene GRB2 and Familial prostate cancer.