MGAM and triple-A syndrome: In general, renal handling of OX and AGEs did not appear to be impaired in this study as basal clearance and excretion were similar to other human studies [12,13] and clearance of OX and AGEs (i.e., MetSO, AAA, CEL, G-H1, and MG-H1) increased substantially in response to the hyperglycemic challenge.