UCP2 and status epilepticus: With this status epilepticus model, we demonstrated that activation of peroxisome proliferator-activated receptor γ (PPARγ) increased mitochondrial UCP2 expression, decreased mitochondrial translocation of Bax, reduced cytosolic release of cytochrome c by stabilizing the mitochondrial transmembrane potential, and lessened apoptotic neuronal cell death in the hippocampus [43].