As PGC-1α is a key player in mitochondrial biogenesis in various neurological conditions [46,54] and resveratrol increased PGC-1α expression and mitochondrial biogenesis in the present study, it is tempting to speculate that there is an intimate relationship between resveratrol and mitochondrial biogenesis machinery expression following status epilepticus. This evidence concerns the gene PPARGC1A and status epilepticus.