After unilateral microinjection of kainic acid (KA) into the left CA3 region, real-time PCR analysis (Figure 1A) revealed that pgc-1α mRNA have a significant increase in the right hippocampal CA3 subfield 1 h after the induction of experimental status epilepticus, followed by a significant reduction that returned to baseline at 24 h. This evidence concerns the gene PPARGC1A and status epilepticus.