LEP and anorexia nervosa: Anorexia nervosa is associated with numerous neuroendocrine dysfunctions associated with modified plasma hormone levels and blunted, suppressed or paradoxical responses to dynamic tests, involving the hypothalamic-pituitary-gonadal growth hormone (GH)-insulin-like growth factor-I (IGF-I) and the hypothalamic-pituitary-adrenal axis, thyroid function, several adipokines, such as leptin, gut peptides such as ghrelin and YY peptide, and the posterior pituitary (oxytocin and anti-diuretic hormone).