In the studies of Zhu et al. [28], liraglutide reduced the area of ischemia caused by MCAO (middle cerebral artery occlusion), limited neurological deficits, decreased hyperglycemia caused by stress, and presented anti-apoptotic effects by causing an increase in the expression of Bcl-2 and Bcl-xlproteins and reduction of Bax (bcl-2-like protein 4) and Bad protein production. This evidence concerns the gene BAX and ischemia.