The master transcriptional regulator is SREBP‐1c, and suppressing SREBP‐1c in cancer cells prevents fatty acid synthesis, leading to inhibition of cancer cell proliferation.37, 38 In addition, increasing lines of evidence suggest that the hyperactivation of YAP, due to inactivation of Hippo signalling, promotes cell proliferation and acts as a tumour promoter in many organs.7 Thus, it is tempting to speculate that YAP‐SREBPs complex may regulate tumorigenesis through controlling cell lipogenesis genes. The gene discussed is YAP1; the disease is cancer.