BRCA1 and breast cancer: The result of Vreeman et al. [18] demonstrated that MRI surveillance is insufficient for BRCA1 mutation carriers because the sensitivity of a combined annual MR examination with mammography breast cancer screening program in BRCA1 mutation carriers was the lowest (81.3%) compared with other groups (BRCA2, 92.0%; family history, 95.2%; personal history, 91.1%).