Apart from complete handover of anesthesia care, univariate analyses identified nine other factors that were associated with the risk of delirium development after surgery, including age, BMI, previous stroke, preoperative albumin < 30 g/L, intraoperative etomidate, ICU admission with intubation, prophylactic dexmedetomidine, postoperative propofol within 7 days, and pathologically diagnosed cancer (Online Resource 2). This evidence concerns the gene ALB and Stroke.