Inverse relations between GDF-15 levels and testosterone were noted for almost all strata, stratified by categories of CAD risk factors, such as hs-CRP, leukocytes, neutrophils, neutrophil to lymphocyte ratio, glucose, HDL-c, and LDL-c and whether had hypertension, diabetes, and underwent PCI. The gene discussed is GDF15; the disease is hypertensive disorder.