CD8A and neoplasm: As shown in Fig. 4A and B, tumor specific CD8+IFN-γ+ T cells were significantly generated in a mouse vaccinated with RPS3-activated DCs pulsed with either OVA or E7 antigenic peptides, as compared to mice vaccinated with immature DCs or non-peptide pulsed mature DCs (OVA and E7 are well known antigens expressed in EG.7 and TC-1 cells respectively).