Focusing on luminal A tumours, Holm et al. also noted worse 10-year overall survival for CCND1-amplified luminal A tumours in univariate analysis [13] (n = 12 CCND1-amplified and 78 non-amplified) as did Chin et al. when examining the amplification status of the 11q13 CCND1 amplicon with a median overall survival follow-up of 6.6 years [38]. Here, CCND1 is linked to neoplasm.