And RANKL, RANKL/OPG, RANK and adipoR1 in control groups (0.70 ± 0.63, 0.80 ± 0.96, 0.66 ± 0.38, 0.51 ± 0.29) were significant lower than AIS groups. Here, TNFSF11 is linked to androgen insensitivity syndrome.