As shown in Table 1, There was no significant relationship between VEGFR2 or VTN expression and gender (P = 0.331), age(P = 0.427), Tumor size (P = 0.153), Lauren type(P = 0.739) and tumor differentiation(P = 0.912),but both of the two genes were colsely related with T staging, N staging and disease stage (P < 0.01). This evidence concerns the gene KDR and neoplasm.