ITGA5 and gliosarcoma: Overexpression of genes related to integrin complexes ITGA5-ITGB1-CAL4A3 and ITGB1-NRP1 in gliosarcomas when compared to GBMs (Table 3) suggest that gliosarcomas are more migratory, invasive tumors, as these integrins are involved into epithelial to mesenchymal transition processes [34,35].