TNC and metabolic dysfunction-associated steatotic liver disease: The excessive reactive oxygen species (ROS) participate in the development of NAFLD through different mechanisms, including lipid peroxidation and the subsequent activation of the nuclear transcription factor-κB (NF-κB) as well as the activation of hepatic stellate cells (HSC), the primary source of extracellular matrix (ECM) proteins such as collagen or tenascin C (TNC) [6].